Perspiration will affect all makeup prosthetic adhesives, and Skin Tite® is no exception. Using a barrier on the skin such as Premiere Products Top Guard or Michael Davy's Sweat Stop before using Skin Tite® will help adhesion.
Another recommendation is to wait until the Skin Tite® silicone is more fully cured before applying the piece. Often times people apply the piece when the Skin Tite® is uncured, causing their model to begin to perspire right away. Waiting a few minutes until the Skin Tite® is more cured can help.